Mitigation of intrahepatic cholestasis induced by 17α-ethinylestradiol via nanoformulation of Silybum marianum L.

"Declarations Ethics approvalTBRI Research Ethics Committee approved this study under number (FWA0010609; PT 633). The Animals conducted the animal experiment (Scientific Procedures) Act, 1986 of the United Kingdom and its related regulations, as well as EU Directive 2010/63/EU for animal research (Publication No. 85 − 23, updated 1985). The study is reported in accordance with ARRIVE guidelines. All methods were carried out in accordance with relevant guidelines and regulations. Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding The authors declare that no funds, grants, or other support were received during the preparation of this manuscript. Open access funding provided by The Science, Technology & Innovation Funding Authority (STDF) in cooperation with The Egyptian Knowledge Bank (EKB)."