Distinct Clinical Effects of Two RP1L1 Hotspots in East Asian Patients With Occult Macular Dystrophy (Miyake Disease): EAOMD Report 4.

"Disclosure: Y. Fujinami-Yokokawa, None; K. Joo, None; X. Liu, None; K. Tsunoda, None; M. Kondo, None; S.J. Ahn, None; A.G. Robson, None; I. Naka, None; J. Ohashi, None; H. Li, None; L. Yang, None; G. Arno, None; N. Pontikos, Phenopolis Ltd. (F); K.H. Park, None; M. Michaelides, None; H. Tachimori, None; H. Miyata, None; R. Sui, None; S.J. Woo, Samsung Bioepis (C), Curacle (C), Novelty Nobility (C), Sometech (C), Novartis (F), Bayer (F), Alteogen (F), Janssen (F), Abbvie (F), Philophos (F), Retimark (F); K. Fujinami, Astellas Pharma (C, F), Kubota Pharmaceutical Holdings (C), Acucela (C), Novartis AG (C, F), Janssen Pharma (C, F), Saliogen therapeutics (C), Alnylam pharmaceuticals (C), Belite Bio (C), FREST (C), Restore Vision (C), Aavantgarde Bio (C), Takara Bio, Inc., Chugai Pharmaceutical Co., LTD."

"Supported by grants from Grant-in-Aid for Young Scientists of the Ministry of Education, Culture, Sports, Science and Technology, Japan (18K16943) (YF-Y); JSPS KAKENHI Grant Numbers 21J21086, 22KJ2665 (Research Fellowships for Young Scientists [DC1], Japan) (YF-Y); Japan Agency for Medical Research and Development (AMED), the Ministry of Health, Labor and Welfare, Japan (18ek0109282h0002), Grants-in-Aid for Scientific Research, and Japan Society for the Promotion of Science, Japan (H26-26462674) (KT); National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology (AGR); a Fight for Sight (UK) Early Career Investigator Award, NIHR-BRC at Moorfields Eye Hospital and the UCL Institute of Ophthalmology, and Great Britain Sasakawa Foundation Butterfield Award, UK (GA); grants from Foundation Fighting Blindness (CD-CL-0214-0631-PUMCH), CAMS Innovation Fund for Medical Sciences (CIFMS 2016-12M-1-002), and National Natural Science Foundation of China (81470669) (RS); a research grant from the Seoul National University Bundang Hospital (02-2017-059) and the National Research Foundation of Korea Grant 2016R1D1A1B03934724, funded by the Korean government (Ministry of Science, ICT and Future Planning) (SJW); grants from the National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, and The Wellcome Trust (099173/Z/12/Z) (MM); and a Grant-in-Aid for Young Scientists (A) of the Ministry of Education, Culture, Sports, Science and Technology, Japan (16H06269), grants from a Grant-in-Aid for Scientists to support international collaborative studies of the Ministry of Education, Culture, Sports, Science and Technology, Japan (16KK01930002), grants from National Hospital Organization Network Research Fund, Japan (H30-NHO-Sensory Organs-03), grants from the Foundation Fighting Blindness Alan Laties Career Development Program (CF-CL-0416-0696-UCL), grants from Health Labour Sciences Research Grant, AMED (23EK0109634H0001, 23EK0109632H0001), The Ministry of Health Labour and Welfare, Japan (201711107A, 23809955, 23FC1056), grants from Great Britain Sasakawa Foundation Butterfield Awards, UK, and grant from National Institute of Health and Care Research (AI AWARD 02488) (KF). Laboratory of Visual Physiology, Division for Vision Research, National Institute of Sensory Organs, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan, is supported by grants from Astellas Pharma Inc (NCT03281005), Jansen Pharma (NCT04868916), and National Institute for Health and Care Research (NIHR), outside the submitted work. The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication."