Multimodal profiling of chordoma immunity reveals distinct immune contextures.

"the rna sequencing data generated in this study are publicly available on geo (gse239531). furthermore differential gene expression analysis revealed enrichment for other immune-related genes in chordomas in comparison with the other sarcomas ( online supplemental figure 1ab online supplemental table 4 ) 10 1136/jitc-2023-008138 supp2 supplementary data 10 1136/jitc-2023-008138 supp3 supplementary data to substantiate that immune-related processes are enriched in chordomas we evaluated the expression of genes included in the icr gene signature to compare between the distinct sarcoma subtypes. data availability statement data are available in a public open access repository. the rna sequencing data generated in this study are publicly available on geo (gse239531"

"Competing interests: No, there are no competing interests."

"Funding: This work was financially supported by the intramural Leiden Center for Computational Oncology strategic fund. NFCCdM is funded by the European Research Council (ERC) under the European Union’s Horizon 2020 Research and Innovation Program (grant agreement no. 852832) and by the VIDI ZonMW (project number: 09150172110092). JVMGB is the recipient of a Cancer Research Institute/Chordoma Foundation CLIP Grant (CRI5106)."