Safety and short-term outcomes of a modified valvuloplastic esophagogastrostomy versus gastric tube anastomosis after laparoscopy-assisted proximal gastrectomy: a retrospective cohort study.

"Declarations DisclosuresBailong Li, Yinkui Wang, Zhouqiao Wu, Fei Shan, Shuangxi Li, Yongning Jia, Rulin Miao, Zhemin Li, Kan Xue, Chao Yan, Shen Li, Jiafu Ji and Ziyu Li have no conflicts of interest or financial ties to disclose. Disclosures Bailong Li, Yinkui Wang, Zhouqiao Wu, Fei Shan, Shuangxi Li, Yongning Jia, Rulin Miao, Zhemin Li, Kan Xue, Chao Yan, Shen Li, Jiafu Ji and Ziyu Li have no conflicts of interest or financial ties to disclose."

"Funding This study was funded by Beijing Nova Program (20220484111), Beijing Hospitals Authority Innovation Studio of Young Staff Funding Support (202123) and Science Foundation of Peking University Cancer Hospital (PY202335)."

"This study is a retrospective cohort study to compare the safety and short-term outcomes of patients who underwent arch-bridge anastomosis and gastric tube anastomosis after laparoscopy-assisted proximal gastrectomy (LAPG) in the Department of Gastrointestinal Surgery Ward One, Peking University Cancer Hospital between November 2021 and April 2023. The inclusion criteria were: (1) histologically proven proximal gastric cancer or adenocarcinoma of the esophagogastric junction; (2) patients who received LAPG with arch-bridge anastomosis or gastric tube anastomosis. Exclusion criteria were: (1) preoperative chemoradiation therapy; (2) open proximal gastrectomy; (3) combined with thoracotomy. The flowchart of the patients’ selection is shown in Fig. . The reconstruction method, either arch-bridge anastomosis or gastric tube anastomosis, was decided based on each patient’s preference after sufficient description of both procedures. If a patient could not decide on the reconstruction method, the chief, and the surgeon would determine the reconstruction method based on the actual operative circumstances. Preoperative assessment of all patients was performed by a multidisciplinary team. All patients were operated on by an experienced surgical team. The team’s chief surgeon (Ziyu Li) owned over 20 years of clinical practice and experience of over 1000 cases of laparoscopic procedures. This study was approved by the institutional review board of the Peking University Cancer Hospital medical ethics committee (No. 2023YJZ11), and written informed consent was obtained from each patient. This study was registered on the ClinicalTrials with the registration number NCT05829213. The study protocol is provided in the Supplementary File. This study was reported in line with STROCSS criteria [].Fig. 1The flowchart of the patients’ selection"