Zhuifeng Tougu capsules in the treatment of knee osteoarthritis (cold dampness obstruction syndrome): a randomized, double blind, multicenter clinical study.

"Declarations Ethics approval and consent to participateThis study has been reviewed by the Ethics Committee of the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine (No. TYLL2019 [Y] No.016), and informed consent was obtained from all subjects involved in the study. Consent for publicationAll the authors listed have approved the manuscript that is enclosed. Competing interestsThis research was jointly funded by the government unit Changsha Science and Technology Bureau and Tiandi Hengyi Pharmaceutical Co., Ltd. All authors declare that the study was conducted without any commercial or financial relationships that could be interpreted as potential conflicts of interest. Competing interests This research was jointly funded by the government unit Changsha Science and Technology Bureau and Tiandi Hengyi Pharmaceutical Co., Ltd. All authors declare that the study was conducted without any commercial or financial relationships that could be interpreted as potential conflicts of interest."

"Funding This work was supported by The Traditional Chinese Medicine Inheritance and Innovation “Hundred Million” Talent Project (Qihuang Project) (Chinese Medicine People’s Education Letter [2018] No. 12)-Liu Wei Qihuang Scholar Studio Construction Project, and The Famous Old Chinese Medicine Inheritance Studio of the State Administration of Traditional Chinese Medicine (975022), and Major special funds for science and technology in Changsha in 2019 (No. 39)."

"Trial registration : Clinical trial registration was completed with the China Clinical Trial Registration Center for this research protocol (No. ChiCTR2000028750) on January 2, 2020."