Lessons Learned from Translating Genome Sequencing to Clinical Routine: Understanding the Accuracy of a Diagnostic Pipeline.

"all the data presented in this work were processed with our data analysis pipeline megsap megsap is freely available at https://github com/imgag/megsap .; data availability statement all data presented in this work were processed with our data analysis pipeline megsap megsap is freely available at https://github com/imgag/megsap . table s1 . raw data"

"all the data presented in this work were processed with our data analysis pipeline megsap megsap is freely available at https://github com/imgag/megsap .; all qc steps described here were performed using tools from ngs-bits which is freely available at https://github com/imgag/ngs-bits .; data availability statement all data presented in this work were processed with our data analysis pipeline megsap megsap is freely available at https://github com/imgag/megsap ."

"Conflicts of Interest The authors declare no conflict of interest."

"J.P. was supported by the Clinician Scientist program “PRECISE.net” funded by the Else Kröner–Fresenius–Stiftung."