Clonorchis sinensis infection amplifies hepatocellular carcinoma stemness, predicting unfavorable prognosis.

"to solidify these findings further endeavors should encompass large multicenter randomized controlled studies and comprehensive investigations into the intricate mechanisms at play s1 data (xlsx) click here for additional data file."

"The authors have declared that no competing interests exist."

"MF received financial support from the National Science Foundation of China (NO. 8236080196, https://www.nsfc.gov.cn/; NO. 31900681, https://www.nsfc.gov.cn/), the National Science Foundation of Guangxi (NO. 2022GXNSFAA035510, http://kjt.gxzf.gov.cn/zwfw/bsxx/xmlxgg/; NO. 2023GXNSFAA026201, http://kjt.gxzf.gov.cn/zwfw/bsxx/xmlxgg/) and the Postdoctoral Science Foundation of China (NO. 2021M693803, https://www.chinapostdoctor.org.cn/bshjjh). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."