Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected.

Publication Year: 2024

DOI:
10.1186/s12879-024-08973-2

PMCID:
PMC10823747

PMID:
38287287

Journal Information

Full Title: BMC Infect Dis

Abbreviation: BMC Infect Dis

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Communicable Diseases

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Evidence found in paper:

"availability of data and materials parasite and host rnaseq data and processed counts have been deposited in the national center of biotechnology information's gene expression omnibus (geo) available under geo accession number gse240643 and gse241467 respectively. all mass spectrometry raw files associated with this study are provided in the online dryad repository ( https://datadryad org/stash/share/8jlf_ceeqfj8b1ftcglyzxyu-rq4c7yddzw2pa4buge ). availability of data and materials parasite and host rnaseq data and processed counts have been deposited in the national center of biotechnology information's gene expression omnibus (geo) available under geo accession number gse240643"

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Evidence found in paper:

"Declarations Ethics approval and consent to participateWritten informed consent was obtained from parents/guardians of the study participants prior to their inclusion in the study. Ethical approval was sourced from the Kenya Medical Research Institute (KEMRI) Scientific Ethics and Review Unit (SERU), under protocol number 3149. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

Evidence found in paper:

"Funding This work was supported through the DELTAS Africa Initiative (Grant No. DEL‑15‑003), an independent funding scheme of the African Academy of Sciences (AAS) Alliance for Accelerating Excellence in Science in Africa (AESA) and supported by the New Partnership for Africa’s Development Planning and Coordinating Agency (NEPAD Agency) with funding from the Wellcome Trust and the UK government, DELGEME Grant 107740/Z/15/Z to support KK. The views expressed in this publication are those of the author(s) and not necessarily those of AAS, NEPAD Agency, Wellcome Trust or the UK government. Jean Langhorne is supported by the Francis Crick Institute which receives its core funding from Cancer Research UK (CC2079), the UK Medical Research Council (CC2079), and the Wellcome Trust (CC2079). There was also support from Wellcome Trust Intermediate Fellowships, Grant Numbers 107568/Z/15/Z and 209289/Z/17/Z awarded to LIO‑O and AA, respectively."

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Last Updated: Aug 05, 2025