SRGN amplifies microglia-mediated neuroinflammation and exacerbates ischemic brain injury.

"Declarations Ethics approval and consent to participateAll animal experiments were performed under the guidance of the Animal.Care Committee of Nanjing University (approval number: 2023AE01024). Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing financial interests or personal relationships that could have appeared to affect the work reported in this paper. Competing interests The authors declare that they have no competing financial interests or personal relationships that could have appeared to affect the work reported in this paper."

"Funding This research was supported by the National Natural Science Foundation of China (81920108017, 82130036), the STI2030-Major Projects (2022ZD0211800), Jiangsu Province Key Medical Discipline (ZDXK202216), and the Key Research and Development Program of Jiangsu Province of China (BE2020620)."