DEAD-Box Helicase 17 exacerbates non-alcoholic steatohepatitis via transcriptional repression of cyp2c29, inducing hepatic lipid metabolism disorder and eliciting the activation of M1 macrophages.

Authors:
Ning D; Jin J; Fang Y; Du P; Yuan C and 11 more

Journal:
Clin Transl Med

Publication Year: 2024

DOI:
10.1002/ctm2.1529

PMCID:
PMC10835191

PMID:
38303609

Journal Information

Full Title: Clin Transl Med

Abbreviation: Clin Transl Med

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Biomedical Engineering

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Data Sharing
Code Sharing
Evidence found in paper:

"CONFLICT OF INTEREST STATEMENT The authors declare that they have no conflict of interest."

Evidence found in paper:

"We are grateful to those patients for donating their liver tissues for the studies. We would like to thank Editage (www.editage.cn) for English language editing. This work was supported by The National Natural Science Foundation of China (No. 8187111473, 8217113337 to Wanguang Zhang) and State Key Project on Infection Disease of China (No. 2018ZX10723204‐003 to Bixiang Zhang)."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025