Integrated multi-omics reveal gut microbiota-mediated bile acid metabolism alteration regulating immunotherapy responses to anti-α4β7-integrin in Crohn's disease.

Authors:
Han B; Tang D; Lv X; Fan J; Li S and 9 more

Journal:
Gut Microbes

Publication Year: 2024

DOI:
10.1080/19490976.2024.2310894

PMCID:
PMC10854365

PMID:
38312103

Journal Information

Full Title: Gut Microbes

Abbreviation: Gut Microbes

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Gastroenterology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Evidence found in paper:

"data availability statement the data obtained from whole-genome shotgun metagenomics and 16s-rdna gene high-throughput sequencing were uploaded to the ncbi sra ( www ncbi nlm nih gov ) and can be accessed using the following bioproject numbers: prjna1022859 prjna1024074 prjna1024099 and prjna1024450.; the data generated from non-targeted metabolomics and targeted ba metabolomics were deposited in the metabolights ( www ebi ac uk/metabolights ) and can be accessed using the following numbers: mtbls8700 and mtbls8702."

Code Sharing
Evidence found in paper:

"Disclosure statement No potential conflict of interest was reported by the author(s)."

Funding Disclosure
Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025