Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice.

"Competing Interests K.L.H. and W.L.S. declare commercial interest in the development of mitochondrial uncouplers as therapeutics through patents and equity interest in Life Biosciences Inc and Uncoupler Biosciences. All other authors have no conflicts of interest."

"Funding EchoMRI data presented in this work was acquired at the Biological Resources Imaging Laboratory of the Mark Wainwright Analytical Centre, UNSW Sydney, which is in part funded by the Research Infrastructure Programme of UNSW. This work was supported by a National Health and Medical Research Council (NHMRC) Ideas Grant [grant number GNT2011004 (to K.L.H.)] and a US National Institutes of Health (NIH) RO1 Grant [grant number DK128612 (to W.L.S. and K.L.H.)]. S-Y.C. and S.J.A. were supported by UNSW Scientia PhD Scholarships. F.L.B is supported by a Cancer Institute NSW Career Development Fellowship (2021/CDF1120)"