Enzyme-like biomimetic oral-agent enabling modulating gut microbiota and restoring redox homeostasis to treat inflammatory bowel disease.

"Declaration of competing interest All authors declare that there are no competing interests."

"This work was supported by the 10.13039/501100001809National Natural Science Foundation of China (Grant Nos.32030061,32271384), Shanghai 10.13039/100011259International Cooperation Project (No.23490712900) and the Basic Research Program of Shanghai Municipal Government (Grant No. 21JC1406000). Zhangpeng Shi: Writing – original draft, Validation, Methodology, Investigation, Formal analysis, Data curation, Conceptualization. Xiaohong Li: Validation, Methodology, Investigation, Formal analysis, Data curation. Jufeng Chen: Validation, Methodology, Investigation, Formal analysis. Zideng Dai: Software, Resources, Methodology, Formal analysis. Yefei Zhu: Software, Resources, Formal analysis. Tan Wu: Software, Resources. Qing Liu: Investigation, Methodology. Huanlong Qin: Writing – review & editing, Supervision, Funding acquisition, Conceptualization. Yang Zhang: Writing – review & editing, Supervision, Funding acquisition, Conceptualization. Hangrong Chen: Writing – review & editing, Supervision, Funding acquisition, Conceptualization."