Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease.

"the following steps were performed using an in-house algorithm developed for array tomography image processing and analysis freely available (based on [ ] available at https://github com/spires-jones-lab fig s1).; data availability protocols image analysis scripts and r scripts for statistical analysis are available at 10 7488/ds/7664."

"Declarations Conflict of interestTSJ is a member of the Scientific Advisory Board of Cognition Therapeutics and Scottish Brain Sciences. NI, LW, and SC were employees of Cognition Therapeutics, and MEH and AOC are current employees of Cognition Therapeutics. Conflict of interest TSJ is a member of the Scientific Advisory Board of Cognition Therapeutics and Scottish Brain Sciences. NI, LW, and SC were employees of Cognition Therapeutics, and MEH and AOC are current employees of Cognition Therapeutics."

"Funding This work was supported by Alzheimer’s Society (project grant AS-PG-15b-023), Alzheimer’s Research UK, the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement No. 681181), the University of Edinburgh (Chancellor’s Fellow start-up funding), Wellcome Trust Institutional Strategic Support Fund, the UK Dementia Research Institute which receives its funding from DRI Ltd., funded by the UK Medical Research Council, Alzheimer’s Society, and Alzheimer’s Research UK (UKDRI-Edin005), and BBSRC Institute Strategic Programme funding."