Patients with obesity have more inflamed joints and higher CRP levels during the disease course in ACPA-positive RA but not in ACPA-negative RA.

"additional file 1: supplementary figure 1. overview of patient selection. supplementary figure 2. raw data"

"Declarations Ethics approval and consent to participate‘Commisie Medische Ethiek’ of the Leiden University Medical Centre (B19.008) Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding The research leading to these results has received funding from the Dutch Arthritis Foundation and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (starting grant, agreement no. 714312). The funding source had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; or decision to submit the manuscript for publication."