The effects of etidronate on brain calcifications in Fahr's disease or syndrome: rationale and design of the randomised, placebo-controlled, double-blind CALCIFADE trial.

Journal Information

Full Title: Orphanet J Rare Dis

Abbreviation: Orphanet J Rare Dis

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Medicine

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Evidence found in paper:

"Declarations Ethics approval and consent to participateThis study has received ethical approval from the Dutch Medical Ethical Review Committee NedMec (registration number 22-1005/Gm-G) and from the Dutch Central Committee on Research Involving Human Subjects (CCMO). Written informed consent will be obtained from all participants. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

Evidence found in paper:

"Funding This study has received funding from the Dutch Brain Foundation (in Dutch: Hersenstichting, grant number DR-2021-00387). The funder had no role in the design of this study and will not have any role during its execution, analyses, and interpretation of the data."

Evidence found in paper:

"Trial registration ClinicalTrials.gov, NCT05662111. Registered 22 December 2022, https://clinicaltrials.gov/ct2/show/NCT01585402."

Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025