The impact of prior exposure to hypoglycaemia on the inflammatory response to a subsequent hypoglycaemic episode.

"Declarations Competing interestsC.E.M.V.: None. J.I.P.v.H.: None. T.W.F.: None. R.S.: None. S.T.: None. C.J.T.: None. B.E.d.G. has received research support from Novo Nordisk. U.P.-B. has served on advisory boards for Sanofi-Aventis and Novo Nordisk and has received lecture fees from Abbott, Sanofi-Aventis and Novo Nordisk. R.J.M. has received lecture fees from Sanofi-Aventis and Novo Nordisk. Competing interests C.E.M.V.: None. J.I.P.v.H.: None. T.W.F.: None. R.S.: None. S.T.: None. C.J.T.: None. B.E.d.G. has received research support from Novo Nordisk. U.P.-B. has served on advisory boards for Sanofi-Aventis and Novo Nordisk and has received lecture fees from Abbott, Sanofi-Aventis and Novo Nordisk. R.J.M. has received lecture fees from Sanofi-Aventis and Novo Nordisk."

"Funding This study has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under Grant Agreement No 777460. The JU receives support from the European Union’s Horizon 2020 research and innovation program and EFPIA and T1D Exchange, JDRF, International Diabetes Federation (IDF), The Leona M. and Harry B. Helmsley Charitable Trust."

"Clinical Trial information Clinicaltrials.gov no. NCT03976271 (registered 5 June 2019)."