Tissue of origin prediction for cancer of unknown primary using a targeted methylation sequencing panel.

"Declarations Ethics approval and consent to participateThe retrospective study was approved by the Ethical Committee of The First Affiliated Hospital of Zhengzhou University. The study participants gave written informed consent before sample collection. Competing interestsBo Xu, Youjie Zhu and Xiaomo Li are employees of Oriomics Biotech Inc. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Competing interests Bo Xu, Youjie Zhu and Xiaomo Li are employees of Oriomics Biotech Inc. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest."

"Funding This study was supported by the Henan Young and Middle-aged Talents in Health Science and Technology Innovation (YXKC2022015)."