COSMIC-based mutation database enhances identification efficiency of HLA-I immunopeptidome.

"availability of data and materials the raw ms-based sequencing files of hepg2 hla-i immunopeptidome have been deposited to iprox integrated proteome resources with identifier ipx0007010000 proteomexchange identifier pxd045203."

"Declarations Ethics approval and consent to participateNot applicable. Consent for publicationThe corresponding author has received consent for publication. Competing interestsThe authors declare no potential conflicts of interest. Competing interests The authors declare no potential conflicts of interest."

"Funding This work was funded by the MOST (2022YFA1304600 and 2020YFE0202200), the National Natural Science Foundation of China (NSFC) (32141003, 32101190, 32070668 and 32071431); the CAMS Innovation Fund for Medical Sciences (2019-I2M-5–017 and 2022-I2M-C&T-B-082), the Foundation of State Key Lab of Proteomics (SKLP-K201704, SKLP-C202002 and SKLP-K201901); and the Mass Spectrometry Platform Open Project of National Center for Protein Sciences Beijing (2021-NCPSB-001)."