Statistical optimization of hydrazone-crosslinked hyaluronic acid hydrogels for protein delivery.

"Conflicts of interest A. N. G., J. D., V. R. S., and M. H. H. are authors on a pending patent application encompassing some of this work."

"We are grateful for funding from the Collins Medical Trust, National Institutes of Health (R21-EB032112), and Wu Tsai Human Performance Alliance. JD is supported by a doctoral-level post-graduate scholarship (PGS-D) from the Natural Sciences and Engineering Research Council of Canada (NSERC). EAM and JK were supported by the Knight Campus Undergraduate Scholars Program. MF was supported by the University of Oregon's Summer Program in Undergraduate Research (SPUR) and Vice President for Research and Innovation (VPRI) Fellowship. We would like to thank Dr Casey Check and Professor Willie (Skip) Rochefort for their guidance on rheology, Patrick Hall for his guidance on scanning electron microscopy, and Professor Danielle Benoit for her guidance on gel permeation chromatography. We would also like to thank Chandler Asnes and Payton Jefferis for their thoughtful feedback on this work."