Identification of a potent and selective LAPTc inhibitor by RapidFire-Mass Spectrometry, with antichagasic activity.
Journal Information
Full Title: PLoS Negl Trop Dis
Abbreviation: PLoS Negl Trop Dis
Country: Unknown
Publisher: Unknown
Language: N/A
Publication Details
Subject Category: Tropical Medicine
Available in Europe PMC: Yes
Available in PMC: Yes
PDF Available: No
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"results for all compounds in the primary rapidfire-ms screen are available in chembl (accession number 5305021).; results for all compounds in the primary rapidfire-ms screen are available in chembl (accession number 5305021).; for this the only laptc 3d structure available in pdb (pdb: 5ntg [ ]) was used to build a functional dimer. s1 file (xlsx"
"The authors have declared that no competing interests exist."
"This research was supported by the following Wellcome awards (203134/Z/16/Z to DWG, MDR, MCF; 204697/Z/16/Z to MCF and 224024/Z/21/Z to DWG, MDR). Wellcome URL: https://wellcome.org/ The funder did not play a role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript."
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Last Updated: Aug 05, 2025