Promising results of a clinical feasibility study: CIRBP as a potential biomarker in pediatric cardiac surgery.

"Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest."

"This study was financially supported by Stiftung KinderHerz Deutschland gGmbH, Essen, Germany (grant number 2511-3-19-020), Deutsche Stiftung für Herzforschung (grant number F/37/20), Frankfurt am Main, Germany and Robert-Enke-Stiftung, Barsinghausen, Germany. We acknowledge support from the German Research Foundation (DFG) and the Open Access Publication Fund of Charité—Universitätsmedizin Berlin. Jana Lücht is participant in the BIH-Charité Junior Clinician Scientist Program funded by the Charité—Universitätsmedizin Berlin and the Berlin Institute of Health at Charité—Universitätsmedizin Berlin."

"This prospective observational feasibility study was conducted at the German Heart Center Berlin after approval by the Ethics Committee of Charité—Universitätsmedizin Berlin, Germany (decision EA2/180/19). The study was registered with the German register for clinical studies before patients' recruitment (registration number: DRKS00020885; https://drks.de/search/de/trial/DRKS00020885). Written consent was obtained from the parents of each patient before study inclusion. Patients younger than 18 years receiving a cardiac surgery at our center were enrolled. Exclusion criteria were as follows: gestational age ≤ 37 weeks, a known maternal alcohol or substance abuse during pregnancy, immunodeficiencies or immunosuppressive medication, syndromic diseases (e.g., Trisomy 21 and 18), and congenital kidney disease."