Importance of quantifying the number of viral reads in metagenomic sequencing of environmental samples from the Huanan Seafood Market.

"as i did in my original study i have provided a fully reproducible computational pipeline ( https://github com/jbloom/huanan_market_samples_addtl_analysis ) as well as interactive plots ( https://jbloom github io/huanan_market_samples_addtl_analysis ) for all new analyses reported in the current paper 5."

"Conflict of interest: J.D.B. is on the scientific advisory boards of Apriori Bio, Aerium Therapeutics, Invivyd, and the Vaccine Company and receives royalty payments as an inventor on Fred Hutch–licensed patents related to deep mutational scanning of viral proteins."

"I thank Liu et al. (2023b) for publicly sharing via the NGDC database the deep sequencing data re-analyzed in this study. This study utilized the Fred Hutch Scientific Computing infrastructure, which is supported in part by National Institutes of Heatlh (NIH) grants S10-OD-020069 and S10-OD-028685. The author is an Investigator of the Howard Hughes Medical Institute."