Tumorigenesis of basal muscle invasive bladder cancer was mediated by PTEN protein degradation resulting from SNHG1 upregulation.

"we have uploaded the raw sequencing data to the shared platform github."

"we have uploaded the raw sequencing data to the shared platform github."

"Declarations Ethics approval and consent to participateNot applicable. Consent for publicationAll authors have agreed to publish this manuscript. Competing interestsThe authors declare that they have no competing interests.Tengda Li, Maowen Huang, Ning Sun, Xiaohui Hua, Ruifan Chen, Qipeng Xie, Shirui Huang, Mengxiang Du, Yazhen Zhao, Qianqian Lin, Jiheng Xu, Xiaoyun Han, Yunping Zhao, Zhongxian Tian, Yu Zhang, Wei Chen, Xian Shen and Chuanshu Huang. Competing interests The authors declare that they have no competing interests. Tengda Li, Maowen Huang, Ning Sun, Xiaohui Hua, Ruifan Chen, Qipeng Xie, Shirui Huang, Mengxiang Du, Yazhen Zhao, Qianqian Lin, Jiheng Xu, Xiaoyun Han, Yunping Zhao, Zhongxian Tian, Yu Zhang, Wei Chen, Xian Shen and Chuanshu Huang."

"Funding This work was partially supported by grants from Natural Science Foundation of China (NSFC81773391 and NSFC81702530) and Oujiang Research Project OJQD2022006 and Discipline Cluster of Oncology, Wenzhou Medical University, China."