A retrospective study on the mechanism underlying quick transfer from response to resistance in a repeated recurrent chordoma patient with molecular alterations treated with Palbociclib.

"the sequencing data are deposited in the genome sequence archive (gsa) for human under accession number prjca017336 ( https://ngdc cncb ac cn/gsa-human ). data availability the data are available from the corresponding author on reasonable request. the sequencing data are deposited in the genome sequence archive (gsa) for human under accession number prjca017336"

"Declarations Conflict of interestNo potential conflicts of interest to report. Informed consentThe investigators of this study had obtained informed consent from the patient for the use of his information for research purposes and for publication. Conflict of interest No potential conflicts of interest to report."

"Funding This study was funded by the National Natural Science Fund Project of China (NSFC No. 82141105 and No. 81902731)."