Low-dose hypomethylating agents cooperate with ferroptosis inducers to enhance ferroptosis by regulating the DNA methylation-mediated MAGEA6-AMPK-SLC7A11-GPX4 signaling pathway in acute myeloid leukemia.

"Declarations Ethics approval and consent to participateOur study was approved by the Ethics Committee of the First Affiliated Hospital of Wenzhou Medical University. All procedures involving animal care and use were in accordance with the National Policy on Use of Laboratory Animals and approved by the Animal Care and Usage Committee of the First Affiliated Hospital of Wenzhou Medical University. Consent for publicationAll of the authors provided written informed consent. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding This research was supported by the National Natural Science Foundation of China (81971991, 82300194) and the Zhejiang Provincial Natural Science Foundation of China (Y23H080009, LY19H080003). Discipline Cluster of Oncology of Wenzhou Medical University of China (z2-2023021)."