Super enhancer related gene ANP32B promotes the proliferation of acute myeloid leukemia by enhancing MYC through histone acetylation.

"the rna-seq data from this study has been deposited in the geo database ( https://www ncbi nlm nih gov/geo ) under accession code gse242850.; rna-seq and cut-tag data have been submitted to the geo database with accession number gse242850."

"Declarations Ethics approval and consent to participateThis study was conducted in accordance with the Code of Ethics of the World Medical Association (Declaration of Helsinki). The studies involving clinical samples were reviewed and approved by the ethics committee of Children’s Hospital of Soochow University. All animal studies were approved by the Animal Care Committee of Suzhou College (Approval number: CAM-SU-AP#: JP-2018-1). Competing interestsThe authors have declared that no competing interests exists. Competing interests The authors have declared that no competing interests exists."

"Funding This work was supported by grants from the National Key R&D Program of China (2022YFC2502700); National Natural Science Foundation (81970163, 81971867, 82072767, 82141110, 82373414, 82300182); Natural Science Foundation of Jiangsu Province (BK20220047, BK20210097); Jiangsu province's science and technology support program (Social Development) project (BE2021657, BE2021654, BE2022732); Suzhou Health Talent Training Project (GSWS2020047, GSWS2021028); the Science and Technology Development Project of Suzhou City (SKJY2021109, SKJY2021111, SKJY2021112, SKY2022170, SKY2022175) and Jiangsu Provincial Health Commission Scientific Research Project (ZD2022056)."