Efficacy of functional magnetic resonance imaging-guided personalized repetitive transcranial magnetic stimulation (fMRI-rTMS) in depressive patients with emotional blunting: study protocol for a randomized controlled trial.

"Declarations Ethics approval and consent to participateThis trial has been approved by the Ethical Committee of Xijing Hospital, Xian, China (approved number: XJLL-KY20222175), and is registered with the ClinicalTrials.gov database (NCT05555940). Any modification of the study protocol will be submitted to the Ethics Committee of Xijing Hospital. Before all patients are enrolled in the study, we will fully explain the purpose of the study, the process of the study, and the risks and benefits of the study. The patients will sign the informed consent form after understanding. Patients participating in this study were completely voluntary and had the right to withdraw at any time. Consent for publicationThe participant information materials and informed consent form are available from the corresponding author on request. Informed consent materials are attached as supplementary materials. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This trial is supported by the National Natural Science Foundation of China (82330043). The funder played no part in study design; collection, management, analysis, and interpretation of data; writing of the report; and the decision to submit the report for publication."

"Trial registration ClinicalTrials.gov INCT05555940. Registered on 13 September 2022 at http://clinicaltrials.gov."