5-Methoxytryptophan enhances the sensitivity of sorafenib on the inhibition of proliferation and metastasis for lung cancer cells.

"Declarations Ethics approval and consent to participateThe authors are accountable for all aspects of the work, ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. All animal experiments were conducted in specific pathogen-free environments, in compliance with the guidelines for the Care and Use of Laboratory Animals. All animal experiments were carried out strictly following the protocols of the Institutional Animal Care and Use Committee (IACUC) of the Scientific Integration Design Service Corporation, Taiwan. The study design and all animal experiments were approved by IACUC of the Scientific Integration Design Service Corporation, and experiments were conducted in compliance with the ARRIVE guidelines. Consent for publicationNot applicable. Competing intereastsThe authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results."

"Funding This work was supported by research grants from the Kaohsiung Medical University (KMHK-DK (整) 109005 ~ 4) and E-Da Hospital (EDAHP112007)."