Tripeptidyl peptidase II coordinates the homeostasis of calcium and lipids in the central nervous system and its depletion causes presenile dementia in female mice through calcium/lipid dyshomeostasis-induced autophagic degradation of CYP19A1.

Authors:
Zhao J; He C; Fan X; Wang L; Zhao L and 12 more

Journal:
Theranostics

Publication Year: 2024

DOI:
10.7150/thno.92571

PMCID:
PMC10879859

PMID:
38389851

Journal Information

Full Title: Theranostics

Abbreviation: Theranostics

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Diagnostic Imaging

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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Evidence found in paper:

"Competing Interests: The authors have declared that no competing interest exists."

Evidence found in paper:

"Funding This work was supported entirely by the intramural program of the Henan Province Mental and Neurological Disease Dominant Discipline Construction Project of Xinxiang Medical University. The content of this manuscript is solely the responsibility of the authors and does not represent the official views of the funding agency."

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Open Access
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Last Updated: Aug 05, 2025