Pharmacokinetic Modeling to Guide Preclinical Development of an Islatravir-Eluting Reservoir-Style Biodegradable Implant for Long-Acting HIV PrEP.

"data availability statement the data presented in this study are openly available online in the national library of medicine pubmed at [ https://doi"

"Conflicts of Interest Authors L.M.J., L.L., A.K. and A.V.D.S. are the inventors of pending patent applications for the implant technology presented in this manuscript. Ariane Van Der Straten is an individual consultant under ASTRA consulting. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest."

"This research was made possible through the support of the U.S. President’s Emergency Plan for AIDS Relief (AID-0AA-A-14-00012 and AID-OAA-A-17-00011) in collaboration with the United States Agency for International Development (USAID). The contents are the responsibility of the authors and do not necessarily reflect the views of RTI, USAID, PEPFAR, or the United States Government. This work was also supported by the University of North Carolina at Chapel Hill Center For AIDS Research (CFAR), an NIH funded program (P30AI050410)."