STING signalling compensates for low tumour mutation burden to drive anti-tumour immunity.

"nanostring genomic data have been deposited under the geo accession number gse190169.; nanostring genomic data are deposited in geo under accession number gse190169.; single-cell sequencing data are deposited in geo under the accession number gse248288 (3' sequence n = 4) and gse255107 (5' sequence n = 11)."

"all scripts used in this publication are available in https://github com/joycetan817/tmb_sting_pancancer ."

"Declaration of interests All authors declare no conflict of interest."

"This work was supported by City of Hope Christopher Family Endowed Innovation Fund for Alzheimer’s Disease and Breast Cancer Research in honour of Vineta Christopher; Breast Cancer Alliance Early Career Investigator Award; National Cancer Institute (NCI) of the National Institutes of Health under award number R01CA256989 and R01CA240392. Research reported in this publication included work performed in the Analytical Cytometry Core, Molecular Pathology Core, Integrated Genomics Core, and Pathology Research Services Core, all supported by the 10.13039/100000054NCI of the 10.13039/100000002National Institutes of Health under award number P30CA033572. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health."