PTHrP intracrine actions divergently influence breast cancer growth through p27 and LIFR.

Publication Year: 2024

DOI:
10.1186/s13058-024-01791-z

PMCID:
PMC10897994

PMID:
38409028

Journal Information

Full Title: Breast Cancer Res

Abbreviation: Breast Cancer Res

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Neoplasms

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Evidence found in paper:

"we identified several hundred significantly altered genes (>= log 2 fold change 1 or <= log 2 fold change - 1 p < 0 05) that were differentially expressed across the pthrp mutants (fig 3 a supplementary data 1 )."

Code Sharing
Evidence found in paper:

"Declarations Ethical approvalExperiments were performed under the regulations of the Animal Welfare Act and the Guide for the Care and Use of Laboratory Animals and approved by the Vanderbilt University Institutional Animal Care and Use Committee (IACUC). Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

Evidence found in paper:

"Funding This work was supported by DoD Breakthrough Award W81XWH-22-1-0090 (R.W.J.). This project was also supported by scholarship funds from NIH award P30CA06848 Vanderbilt-Ingram Cancer Center Support Grant and NIGMS T32GM007347."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025