Expression of red/green-cone opsin mutants K82E, P187S, M273K result in unique pathobiological perturbations to cone structure and function.

"Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision."

"The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by National Institutes of Health (R01 EY030056 to Deng, R01 EY08123 and EY014800-039003 (NEI core grant) to Baehr), West Virginia University startup fund, NIGMS P20GM144230 (Visual Sciences Center of Biomedical Research Excellence), BCM Families Foundation, West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE), unrestricted grants to the University of Utah Department of Ophthalmology from Research to Prevent Blindness (RPB; New York) and the West Virginia Lions and Lions Club International Foundation."