Integrative single-cell transcriptomic analyses reveal the cellular ontological and functional heterogeneities of primary and metastatic liver tumors.

"data availability the processed gene expression data of scrna-seq of primary hcc tumors and non-tumor liver tissues are available at the geo database under the accession code gse149614. data availability the processed gene expression data of scrna-seq of primary hcc tumors and non-tumor liver tissues are available at the geo database under the accession code gse149614"

"Declarations Ethics approval and consent to participateNot applicable. Consent for publicationNot applicable. Competing interestsThe authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Competing interests The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest."

"This work was supported by grants from the National Key Research and Development Plan of China (2022YFC2504703), National Natural Science Foundation of China (No. 82172707 and 82002573). BioRender was used to create Graphics."