Inhibition of MMP8 effectively alleviates manic-like behavior and reduces neuroinflammation by modulating astrocytic CEBPD.

Authors:
Wang TY; Weng EF; Hsu YC; Shiu LP; Huang TW and 3 more

Journal:
J Neuroinflammation

Publication Year: 2024

DOI:
10.1186/s12974-024-03054-2

PMCID:
PMC10900742

PMID:
38419037

View on PubMed View on PMC View Publisher
Journal Information

Full Title: J Neuroinflammation

Abbreviation: J Neuroinflammation

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Neurology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Related Papers from Same Journal
Advanced patient-specific microglia cell models for pre-clinical studies in Alzheimer's disease.
Cuní-López C; Stewart R; Oikari LE and 7 more (2024) - Transparency Score: 5/6
A pre-existing Toxoplasma gondii infection exacerbates the pathophysiological response and extent o…
Baker TL; Wright DK; Uboldi AD and 8 more (2024) - Transparency Score: 3/6
Arachidonic acid-derived lipid mediators in multiple sclerosis pathogenesis: fueling or dampening d…
Broos JY; van der Burgt RTM; Konings J and 5 more (2024) - Transparency Score: 3/6
Associations between sex, body mass index and the individual microglial response in Alzheimer's dis…
Biechele G; Rauchmann BS; Janowitz D and 30 more (2024) - Transparency Score: 3/6
Autoimmune demyelination alters hypothalamic transcriptome and endocrine function.
Carver JJ; Lau KM; Puckett AE and 1 more (2024) - Transparency Score: 3/6
View All Papers from This Journal
Transparency Score
3/6
50.0% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Data Sharing
Code Sharing
Evidence found in paper:

"Declarations Ethics approval and consent to participateAll animal procedures were conducted according to the principles outlined in the China Medical University Guide for the Care and Use of Laboratory Animals (CMUIACUC-2022-062 and CMUIACUC-2023-318). Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

Evidence found in paper:

"Funding This research was funded by the National Science and Technology Council, Taiwan (Grant numbers: MOST 111-2628-B-039-006-MY3, MOST 111-2314-B-006-033-MY3, NSTC 111-2320-B-039 -073 -MY2, and 111-2320-B-039-075). This work was also supported by grant CMU112-MF-05 from China Medical University, Taiwan."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025