Elevated SLC7A2 expression is associated with an abnormal neuroinflammatory response and nitrosative stress in Huntington's disease.

"availability of data and materials rna-seq data were deposited into the geo database under accession number gse241325 and are available at the following url: https://www ncbi nlm nih gov/geo/query/acc cgi? availability of data and materials rna-seq data were deposited into the geo database under accession number gse241325"

"Declarations Ethics approval and consent to participateHuman data used in this work were generously provided by the participants in the Enroll-HD study and made available by CHDI Foundation, Inc. Enroll-HD is a global clinical research platform designed to facilitate clinical research in Huntington’s disease. All sites are required to obtain and maintain local ethical approval. All animal procedures were approved by the Institutional Animal Care and Use Committee of Florida Atlantic University and were in compliance with the National Institutes of Health Guidelines for the Care and Use of Laboratory Animals. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This work was partially supported by the National Institutes of Health (NS111202 to J.W.). J.W. was partially supported by the US National Institutes of Health (EB025819) and Florida Department of Health (9AZ06). The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results."