Multifunctional nanomaterials <i>via</i> cell cuproptosis and oxidative stress for treating osteosarcoma and OS-induced bone destruction.

"Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."

"The study was supported by the 10.13039/501100001809National Natural Science Foundation of China (Grant No. 82002284), the 10.13039/501100014996Health Commission of Zhejiang Province (Grant No. 2021449373), the National Science and Technology Major Project (Grant Nos. 2020YFC1107100). Lin Ye: Conceptualization, Investigation, Methodology, Writing – original draft. Congcong Yu: Methodology, Validation, Writing – original draft. Jiechao Xia: Methodology, Validation. Kainan Ni: Visualization. Yejin Zhang: Supervision. Xiaozhang Ying: Investigation. Dingqi Xie: Validation. Yang Jin: Visualization. Rongtai Sun: Funding acquisition, Writing – original draft. Ruikang Tang: Funding acquisition, Writing – review & editing. Shunwu Fan: Conceptualization, Funding acquisition. Shasha Yao: Conceptualization, Funding acquisition, Writing – review & editing."