The Evidence for the Use of Osteobiologics in Hybrid Constructs (Anterior Cervical Discectomy and Fusion and Total Disc Replacement) in Multilevel Cervical Degenerative Disc Disease: A Systematic Review.

"The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article."

"Funding: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This supplement was organized and financially supported by AO Spine through the AO Spine Knowledge Forum Degenerative, a focused group of international spine experts."

"This study was registered in the International prospective register of systematic reviews (PROSPERO) under the registration number: CRD42020209665. This manuscript has been written according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement. A PRISMA checklist is provided in Supplementary Appendix I. Authors’ Note: This review is part of a series of reviews initiated by AO spine knowledge forum. Systematic review registration number: Registered at PROSPERO (CRD42020209665)."