JMJD3 regulate H3K27me3 modification via interacting directly with TET1 to affect spermatogonia self-renewal and proliferation.

"the chip-seq data discussed in this article have been deposited at ncbi and are available under geo serial registration number gse233150 with the link ( https://www ncbi nlm nih gov/geo/query/acc cgi? data availability the datasets presented in this study can be found in online repositories. the names of the repository/repositories and accession number(s) can be found below: gse233150"

"Declarations Ethics approval and consent to participateThe study received special approval from the Laboratory Animal Ethics Committee of Anhui Medical University (20190371). All methods were performed in accordance with ARRIVE guidelines. Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding This work was supported by the National Natural Science Foundation of China (grant no. 31902225), and the Anhui Province Natural Science Fund Project (grant no. 1908085QC92)."