Deciphering the omicron variant: integrated omics analysis reveals critical biomarkers and pathophysiological pathways.

"Declarations Ethics approval and consent to participateInformed consent was obtained from all participants, and approval was granted by the Ethics Committee of Guangzhou Medical University Affiliated First Hospital (Ethics Numbers: 202001134 and 202115202). Consent for publicationNot applicable. Competing interestsThe authors have declared that no competing interests exists. Competing interests The authors have declared that no competing interests exists."

"Funding Guangdong Zhong Nanshan Medical Foundation (ZNSA-2021005). Guangdong Province Basic and Applied Basic Research Foundation Precision Medicine Joint Foundation (2021B1515230008). Rapid Development and Application of Broad-Spectrum Human Neutralizing Antibodies Against SARS-CoV-2, Zhong Nanshan Medical Foundation of Guangdong Province (2021004). Exploration and Optimization of Early Intervention Strategies and Timing for High-Risk Individuals at Risk of Severe Illness/Death (2022YFC2304803). Enhancing the Treatment and Outcome of COVID-19 Infections through the Use of Medical Consortiums as a Vehicle (ZHYG202339)."