Ubiquitylation of RUNX3 by RNA-binding ubiquitin ligase MEX3C promotes tumorigenesis in lung adenocarcinoma.

"Declarations Ethics approval and consent to participateThe Ethics Committee of Huashan Hospital of Fudan University gave its approval for this study (Ethics No.: 2022-490), and all of the recruited patients gave their informed consent. Consent for publicationWritten informed consent was obtained from all the patients for the study. Competing interestsNone to declare. Competing interests None to declare."

"Funding The study were supported by the First Affiliated Hospital of Bengbu Medical College Science Fund for Distinguished Young Scholars (No. 2019BYYFYJQ04); Bengbu Medical College Science Fund for “Excellent Young Teachers in 512 Talent Development Programme” (No. BY51201314), Natural Science Research Project of Anhui Educational Committee (Nos. KJ2021A0692 and KJ2021A0781); Translation Medicine Key Project of Bengbu Medical College (No. BYTM2019013), Bengbu Medical College Joint Research Project (No. BYLK201810); Yunnan Provincial Science and Technology Department-Applied Basic Research Joint Special Funds of Chinese Medicine [No. 2019FF002(-011)]; The National Natural Science Foundation of China (No. 81602545)."