Induced pluripotent stem cell-derived hepatocytes reveal TCA cycle disruption and the potential basis for triheptanoin treatment for malate dehydrogenase 2 deficiency.

Publication Year: 2024

DOI:
10.1016/j.ymgmr.2024.101066

PMCID:
PMC10900122

PMID:
38425868

Journal Information

Full Title: Mol Genet Metab Rep

Abbreviation: Mol Genet Metab Rep

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Genetics & Heredity

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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"Declaration of competing interest All authors declare no conflicts of interest."

Evidence found in paper:

"Funding DSF is supported by the 10.13039/501100001711Swiss National Science Foundation (310030_192505) and the University Research Priority Program ITINERARE – Innovative Therapies in Rare Diseases. PF is supported by the 10.13039/100004410European Molecular Biology Organization (ALTF 263–2022) and the 10.13039/501100001711Swiss National Science Foundation (P500PB_211038). AL is supported by the Palatin Foundation (0087/2023)."

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Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025