CSF Biomarkers in Longitudinal Alzheimer Disease Cohorts: Pre-Analytic Challenges.

"Authors’ Disclosures or Potential Conflicts of Interest Upon manuscript submission, all authors completed the author disclosure form. Disclosures S.C. Johnson has served as a consultant to Prothena, Eisai, Merck, ALZpath, and Roche Diagnostics, has received an equipment grant from Roche Diagnostics, and has received support (sponsoring of an observational study and provision of precursor for tau imaging) from Cerveau Technologies. B.B. Bendlin and B.T. Christian have received imaging agents and precursor from Avid Radiopharmaceuticals. T.J. Betthauser has received speaking honoraria from Intermountain Healthcare. B.B. Bendlin, advisory board, New Amsterdam Pharma. C.M. Carlsson, Chair, HHS Advisory Council on Alzheimer’s Research, Care, and Services (NAPA Council) and has received travel support for NAPA meetings; honorarium received as Co-Chair NIH/NIA ADRC Program Clinical Task Force Clinical Measures and Diagnosis Subcommittee; received grants to institution: VA Merit 1 I01 CX001261; Armarin Corp (study drugs for VA Merit); NIH/NIA U19 AG010483/Lilly (A4 Trial); NIH/NIA R01 AG049872; Alz Assn/FNIH “LEARN Study”; NIH/NIA R01 AG021155; NIA/NIA R01 AG054059; NIH/NIA U2CAG057441; NIH/NIA RF1AG052324; NIH/NIA R01 AG060737; BAN2401-G000-303 (NIH/Eisai); NIH/NIA 1U19AG065188-01; NIH/NIA 1RF1AG066837; UW Department of Medicine Pilot Funding; NIH/NIA P30 AG062715; NIH/NIA 2RF1 AG027161; honoraria given for talks at Indiana Neurological Society and Northwestern University Medical Grand Rounds; travel funding from Alzheimer’s Association (Chair of US POINTER DSMB) and CTAD (Plenary Speaker at CTAD 2021); honorarium for chairing DSMB for 2 NIH clinical trials (TDAD [U Kansas], D-CARE [UCLA]); Amarin Corp (Vascepa/placebo study drugs for VA-funded trial) study drugs for trial given to institution. R.J. Przybelski, Genentech advisory panel for one meeting. S. Asthana, received NIH/NIA T32 Training Grant; royalty as an editor of a textbook entitled Hazzard's Geriatrics and Gerontology (McGraw-Hill)."

"Research Funding This work was supported by the National Institutes of Health (grant numbers P30AG062715, RO1AG021155, R01AG027161, R01AG037639, R01AG062167, S10 OD025245-01, UL1TR000427), the Alzheimer’s Association, and Roche Diagnostics."