CRISPR/Cas9-edited ROS1 + non-small cell lung cancer cell lines highlight differential drug sensitivity in 2D vs 3D cultures while reflecting established resistance profiles.

Journal Information

Full Title: J Transl Med

Abbreviation: J Transl Med

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Medicine

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
Transparency Indicators
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Core Indicators
Data Sharing
Code Sharing
Evidence found in paper:

"Declarations Ethics approval and consent to participateNot applicable. Consent for publicationNot applicable. Competing interestsC.D. is co-founder of Orbits® Oncology, an image and data analysis platform that was used in this study. Competing interests C.D. is co-founder of Orbits® Oncology, an image and data analysis platform that was used in this study."

Evidence found in paper:

"Funding This project was founded by FWO (Research Foundation Flanders)—"Kom op tegen kanker". Project number: G094820N."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025