NOX4 aggravates doxorubicin-induced cardiomyocyte pyroptosis by increasing reactive oxygen species content and activating the NLRP3 inflammasome.

Authors:
Zeng H; Zou P; Chen Y; Zhang P; Shao L.

Journal:
Cardiovasc Diagn Ther

Publication Year: 2024

DOI:
10.21037/cdt-23-142

PMCID:
PMC10904297

PMID:
38434559

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Journal Information

Journal Title: Cardiovasc Diagn Ther

Detailed journal information not available.

Publication Details

Subject Category: Cardiac & Cardiovascular Systems

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score

3/6

50.0% Transparent

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COI Disclosure

Evidence found in paper:

"Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://cdt.amegroups.com/article/view/10.21037/cdt-23-142/coif). L.S. reports that this study was funded by the National Natural Science Foundation of China (No. 82160053; No. 82260078). The other authors have no conflicts of interest to declare."

Funding Disclosure

Evidence found in paper:

"Funding: This work was supported by the National Natural Science Foundation of China (No. 82260078 to L.S.) and Interventional Therapy Clinical Medical Research Center of Jiangxi Province (No. 20223BCG74005)."

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Open Access

Paper is freely available to read

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Last Updated: Aug 05, 2025