Identification of inhibitors from a functional food-based plant Perillae Folium against hyperuricemia via metabolomics profiling, network pharmacology and all-atom molecular dynamics simulations.

"Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest."

"The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was funded by Joint Funds of National Natural Science Foundation of China [grant number U22A20365], Key Project of National Natural Science Foundation of China [grant number 81830117], Guangzhou Science and Technology Plan Project [grant number 2024B03J1343], National Natural Science Foundation of China [grant numbers 82204812, 82274499], China Postdoctoral Science Foundation [grant number 2022M711534], Guangdong Basic and Applied Basic Research Foundation [grant number 2021A1515110082], Scientific Research Project of Traditional Chinese Medicine Bureau of Guangdong Province [grant number 20221027]."