Comparative bioactivity and immunomodulatory potential of the new Bioroot Flow and AH Plus Bioceramic sealer: An in vitro study on hPDLSCs.

"Declarations Ethical approvalAll procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.The study protocol was approved by the Clinical Research Ethics Committee of the Universidad de Murcia (ID: 3686/2021). Likewise, permission was obtained from the Health Department authorities to use the information contained in the CDHs, previously anonymized by one of the investigators belonging to the medical staff of the Health Department in order to protect patient confidentiality. All the information was processed in abidance with the confidentiality regulations defined under Act 15/1999 referred to personal data protection. Ethics and consent to participateWritten informed consent was obtained from the parents of all individual participants included in the study. Conflicts of interestJL Sanz declares that he has no conflict of interest. S. López-García declares that he has no conflict of interest. D. García-Bernal declares that he has no conflict of interest. FJ. Rodríguez-Lozano declares that he has no conflict of interest. L. Forner declares that he has no conflict of interest. A. Lozano declares that he has no conflict of interest. L. Murcia declares that she has no conflict of interest. Competing interestsThe authors declare no competing interests. Conflicts of interest JL Sanz declares that he has no conflict of interest. S. López-García declares that he has no conflict of interest. D. García-Bernal declares that he has no conflict of interest. FJ. Rodríguez-Lozano declares that he has no conflict of interest. L. Forner declares that he has no conflict of interest. A. Lozano declares that he has no conflict of interest. L. Murcia declares that she has no conflict of interest. Competing interests The authors declare no competing interests."

"Funding Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. This work was supported by the Spanish Network of Cell Therapy (TerCel), RETICS subprograms of the I + D + I 2013–2016 Spanish National Plan, project “RD16/0011/0001” funded by the Instituto de Salud Carlos III to JMM and co-funded by the European Regional Development Fund."