Modified peptides and organic metabolites of cyanobacterial origin with antiplasmodial properties.

"additional structures with dolastatin 10 analogs deposited on the pdb and obtained by x-ray diffraction are available (pdb id: 4x1k and 4x20).; additional structures can be downloaded from the pdb database from s cerevisiae 20s proteasome in complex with ek derivatives such as1g65 and 4no9."

"Declaration of competing interest The authors declare no conflict of interest."

"Funding This work was supported by the 10.13039/501100007487Autonomous University of Mexico City (UACM) awarded to MEAS and the grant of the Colegio de Ciencia y Tecnología for the project UACM CCYT-2023-IMP 03, and to the National Institute of Psychiatry Ramón de la Fuente Muñiz (INPRFM). We appreciate the excellent technical assistance of MsC Laura Vazquez Carrillo and the technical support of Alfredo Padilla of the UACM."