Effect of inulin on breath hydrogen, postprandial glycemia, gut hormone release, and appetite perception in RYGB patients: a prospective, randomized, cross-over pilot study.

"Competing interests The authors declare no competing interests."

"We thank Felix Beuschlein and Natalie Mueller as well as the involved staff from the Endocrinology Department, University Hospital Zurich, for helping with patient recruitment and assisting during the meal studies. We also thank Florian Huwyler from the Federal Institute of Technology Zurich for performing the viscosity experiments. This research was supported by a research grant awarded by the Uniscientia Foundation."

"The study was carried out according to the Declaration of Helsinki. Ethical approval was received from the Cantonal Ethical Committee of Zurich (BASEC-Nr. 2017-02287) and the protocol was registered at ClinicalTrials.gov with Identifier NCT03573258. All patients were informed in detail about the risks and benefits of the surgery and test meals and each provided written, informed consent to participate in the trial. Computer-generated random numbers were used to assign the order of test meals. All operations were performed laparoscopically and by the same surgical team. The RYGB technique consisted of a small gastric pouch with a linearly stapled gastrojejunostomy (30 mm) along with a 150 cm antecolic alimentary limb and a 70 cm of biliopancreatic limb. Table provides subjects BMI and fasting blood glucose and plasma insulin before and after surgery."